Cross My Heart, Hope to Die, Stick a Needle in my Eye

Dr. Hopkins at 11am
Dr. Solsky at 1:00pm
Dr. Dayani at 1:30pm

Dr. Hopkins is anxious to have me start the systemic drugs.  Now, talks of new, more toxic drugs, Cellcept and Cytoxan have crept into the dialogue replacing Plaquenil and Methotrexate.  I was anxious about starting Methotrexate because of its warning to avoid pregnancy while on it because of the horrid birth defects it can cause not knowing what it was doing to my body but compared to the new drugs it was a walk in the park.  Cytoxan is a derivative of mustard gas.

“This potent cell-killing medication is a “nitrogen mustard” derivative, meaning it is related to the toxic chemical weapon “mustard gas” (so named because of its “mustard” or “horseradish” odor) used widely in the first World War. In chemotherapy, cyclophosphamide is classified as an “alkylating agent” which means it works by binding to DNA, and interfering with normal cell function. By disrupting cellular DNA, cyclophosphamide is able to kill the cell. Cells that divide rapidly (and thus replicate their DNA rapidly) are especially targeted by cyclophosphamide.”

Dr. Hopkins isn’t satisfied with just the solumedrol treatment and wants to go forth on the direct injections in the eye after I see the uveitis specialist, Dr. Dayani, and he suggests that the hemorrhaging is ischemic, which means “a decrease in the blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels.”

OMG!!!  I got a needle stuck in my eye.  Literally!  Dr. Dayani injected Kenalog, a steroid, directly into my eye!!!  They wanted to get the steroids to where it was mostly needed and didn’t have the time for the prednisone or solumedrol to work.  We had to take the direct route.  After my eye was prepped, sterilized and numbed, Dr. Dayani took a needle to my eye and I felt a little pinch and pressure and it felt like taking a needle to a slightly deflated balloon.  You get a little bounce back and your imagination takes hold and you think it’s a lot worse than it really is.  And then it was over.  He said I would see swirly clouds of the drug in my eye.  Which I did and it was kind of creepy.  The site of the injection started to bother me a little bit but they had given me pain relieving eye drops to take.

Ugh, I can’t believe that I just got a needle in my eye.

Intravitreal Injection


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